Product Description
Recombinant Human Endostatin 100ug
Description - Recombinant Human Endostatin produced in Pichia Pastoris
is a single, glycosylated, polypeptide having a total molecular mass
of 20,000 Dalton C-terminal fragment of collagen XVIII that has
been shown to act as a potent inhibitor of angiogenesis and
tumor growth in vitro and in vivo. Induces tyrosine
phosphorylation of Shc (SH2 domain adapter protein) leading to
specific inhibition in endothelial cell prolifiration. Recombinant
Endostatin is purified by proprietary chromatographic techniques.
Appearance - Sterile filtered liquid formulation 1mg/ml.
Stability - Human Endostatin although stable at 4 C for 30 days, should
be stored desiccated below -20 C for periods greater than 30 days.
Please avoid freeze-thaw cycles.
Purity - Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel
Publication
